Integrated Analysis to Identify a Redox-Related Prognostic Signature for Clear Cell Renal Cell Carcinoma

Figure 4

Risk score, survival time, and survival status analysis of ccRCC patients based on the fourteen RRGs’ prognostic signature in the TCGA and E-MTAB-1980 cohorts. (a) Kaplan-Meier survival curve analysis of OS in the high- and low-risk subgroups of the TCGA cohort. ccRCC patients were grouped according to the median risk score. (b) Time-dependent ROC curves of the RRG-based risk signature for the TCGA cohort. The ROC curves and AUC were shown to predict ccRCC patients at 1, 3, and 5 years. (c) Kaplan-Meier survival curve analysis of OS in the high- and low-risk subgroups of the E-MTAB-1980 cohort. ccRCC patients were grouped according to the median risk score. (d) Time-dependent ROC curves of the RRG-based risk signature for the E-MTAB-1980 cohort. The ROC curves and AUC were shown to predict ccRCC patients at 1, 3, and 5 years. (e) The survival status of each patient in the TCGA cohort assessed by risk score. (f) The survival status of each patient in the E-MTAB-1980 cohort assessed by risk score. (g) Heat map of the fourteen RRGs in the TCGA cohort was evaluated based on risk score combined with other clinical parameters. (h) Heat map of the fourteen RRGs in the E-MTAB-1980 cohort was evaluated based on risk score combined with other clinical parameters.

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