The Secretome Deregulations in a Rat Model of Endotoxemic Shock

Figure 3

Effect of lipopolysaccharide (LPS) administration on heart rate (HR) and mean arterial blood pressure (MAP). Black and red squares represent the control and LPS rats, respectively. The dotted line represents the threshold considered physiological. The T50 and T90 groups are pooled for both control and LPS conditions ( in the control group and in the LPS group). Only the T90 group is monitored after 50 minutes ( for the T90 control group and for the T90 LPS group). Values represent the of 6 rats per group. (a) Heart rate and (b) MAP were evaluated during 50 or 90 min after LPS injection and were expressed in beats per min (bpm) and mmHg, respectively. The symbol # represents a comparison at a given time between the CT and LPS groups, and the symbol represents a comparison over time for the LPS group. ^#, ^###, and two-way ANOVA test with Bonferroni post hoc test.

(a)

(b)