Research Article

The Oral Delivery of Water-Soluble Phenol TS-13 Ameliorates Granuloma Formation in an In Vivo Model of Tuberculous Granulomatous Inflammation

Table 2

Relationship () between the features of BCG granuloma, the intensity of free-radical oxidation processes, and the expression of the Keap1/Nrf2/ARE signaling pathway genes.

Spontaneous CLLACLH2O2-LACLPECsNfe2l2NQO1Gstp1Hmox1

Spontaneous CLā€”
LACL
H2O2-LACLā€”
PECs
Nfe2l2ā€”
NQO1
Gstp1

: numerical density of granulomas; : diameter of granulomas; CL: chemiluminescence; LACL: luminol-amplified chemiluminescence; H2O2-LACL: H2O2-induced luminol-amplified chemiluminescence; PECS: DCF-dependent fluorescence of PMA-stimulated peritoneal exudate cells; Nfe2l2, NQO1, Gstp1, and Hmox1: mRNA expression of appropriate genes. Significant values.