Neferine Protects against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Suppressing NLRP3-Mediated Inflammasome Activation

<div>Neferine attenuates NLRP3/caspase-1/IL-1<i>β</i> activation in neonatal rat brain tissue after HI. (a) The protein levels of cleaved caspase-1, GSDMD, ASC, NLRP3, IL-1<i>β</i>, and IL-18 were evaluated by Western blotting in brain tissues. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Neferine Protects against Hypoxic-Ischemic Brain Damage in Neonatal Rats by Suppressing NLRP3-Mediated Inflammasome Activation 