Inactivation of TOPK Caused by Hyperglycemia Blocks Diabetic Heart Sensitivity to Sevoflurane Postconditioning by Impairing the PTEN/PI3K/Akt Signaling

<div>Model flow diagram of sevoflurane postconditioning (SPostC) protective effects against myocardial ischemia/reperfusion (IR) injury. (a) Experimental animal models. (b) Schematic presentation of the cell models.</div>

Oxidative Medicine and Cellular Longevity

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Figure 1

Figure 1: Inactivation of TOPK Caused by Hyperglycemia Blocks Diabetic Heart Sensitivity to Sevoflurane Postconditioning by Impairing the PTEN/PI3K/Akt Signaling 

Figure 1 | Inactivation of TOPK Caused by Hyperglycemia Blocks Diabetic Heart Sensitivity to Sevoflurane Postconditioning by Impairing the PTEN/PI3K/Akt Signaling 