The Role of Antioxidants in the Management of Obsessive-Compulsive Disorder

Figure 2

Hypothetical mechanisms of oxidative stress-induced neuronal damage. Abbreviations: COX-2: cyclooxygenase 2; CREB: cAMP response element-binding; GABA: γ-aminobutyric acid; NADPH: nicotinamide adenine dinucleotide phosphate; NFB: nuclear factor B; NO: nitric oxide; NOS: nitric oxide synthase; RNS: reactive nitrogen species; ROS: reactive oxygen species. Reproduced with permission from [15].