SS-31 Protects Liver from Ischemia-Reperfusion Injury via Modulating Macrophage Polarization

Figure 2

SS-31 treatment decreased oxidative stress in the liver after IRI. (a, b) Representative images of DHE staining in liver sections undergoing IRI treated with or without SS-31 ( per group). (c) Representative 8-OHDG immunohistochemistry of liver sections with or without IRI ( per group). (d) The mRNA levels of genes related to liver oxidative stress were measured. (e) The activity of MnSOD was detected by using the Superoxide Dismutase (SOD) Activity Assay Kit in the liver to assess liver oxidative stress ( per group). (f) Immunoblot analysis of HO-1 and SOD2 expression in the liver ( per group). Scale bars, 100 μm. Data are , , , , and by unpaired Student’s -test.

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