Review Article

Enhancing the Therapeutic Potential of Mesenchymal Stem Cells with Light-Emitting Diode: Implications and Molecular Mechanisms

Table 2

Irradiation LED protocol of selected studies.

ReferencesWavelength (nm)Irradiation area (cm2)Potency (mW)Irradiance (mW/cm2)Energy (J)Radiant exposure (J/cm2)Time of irradiation (sec)Irradiation quantityTimeline (days)

[44]6300.321.6
4.8
5
15
0.64
1.28
0.64
1.28
2
4
2
4
400
800
133
266
Once or multiple28
[45]6539#33.573.730.675
1.341
2.016
3.024
4.032
0.075
0.149
0.224
0.336
0.448
20
40
60
90
120
Once15
[46]6601.9#19101.9
3.8
11.4
17.1
1
3
6
9
600Once14
[13]6200.32#2.136.670.32
0.64
0.128
1
2
4
150
300
600
Multiple21
[47]6250.32#0.8482.650.102
0.204
0.305
0.318
0.636
0.954
120
240
360
Once14
[48]6301.9#70.3373.8
7.6
15.2
30.4
60.8
2
4
8
16
32
54
107
214
428
856
Once1
[49]400-8009#3604021.6
43.2
64.8
2.4
4.8
7.2
60
120
180
Once7
[50]6259#47.75.317.11.9360Once21
[51]63375#534
123.75
1.65
7.12
22.5
75
225
450
22.5
75
225
450
0.3
1
2
6
0.3
1
3
6
182
606
1818
3636
42
140
421
843
Once10
[54]420-4809#9001009
18
36
54
1
2
4
6
10
20
40
60
Multiple28

Missing parameters have been calculated. #Data were calculated on the culture flasks/dishes/wells areas.