Research Article

NOX4-Derived ROS Promotes Collagen I Deposition in Bronchial Smooth Muscle Cells by Activating Noncanonical p38MAPK/Akt-Mediated TGF-β Signaling

Table 1

Demographics of COPD patients and healthy cohorts.

DemographicsControl ()COPD () values

Age0.10
Gender (male/female)9/1220/8
WBC (×109/L)0.01
Neutrophils (×109/L)≤0.01
Lymphocytes (×109/L)0.48
NLR0.01
FEV10.02
FVC0.55
FEV1/FVC%≤0.01
FEV1%pred0.04

FEV1: forced expiratory volume in one second; FVC: forced vital capacity; NLR: neutrophil-lymphocyte ratio; WBC: white blood cell.