Chinese Herbal Prescription Fu-Zheng-Qu-Xie Prevents Recurrence and Metastasis of Postoperative Early-Stage Lung Adenocarcinoma: A Prospective Cohort Study Followed with Potential Mechanism Exploration

Figure 3

MDSCs played a key role in the inhibition of tumor progression by the FZQX prescription. Flow cytometry was performed on the percentage of MDSCs, Treg, and NK in spleens and tumor tissues. (a–c) The proportion of CD11b⁺Gr-1⁺ cells in the tumor tissues and spleens was determined (). (d) The proportion of CD₄⁺CD₂₅⁺ cells in the tumor tissues and spleens was determined (). (e) The percentage of Dx5⁺NKG2D⁺ cells in the tumor tissues and spleens was analyzed (). (f) Arg-1 and iNOS mRNA expression levels were quantified by RT-qPCR. (g) The concentration of serum IL-1β and CCL4 were measured by ELISA.

(a)

(b)

(c)

(d)

(e)

(f)

(g)