Superoxide Dismutase 2 (SOD2) in Vascular Calcification: A Focus on Vascular Smooth Muscle Cells, Calcification Pathogenesis, and Therapeutic Strategies

<div>A summary diagram illustrating the regulatory molecules and the effectors of SOD2 in vascular smooth muscle cells demonstrated in the literature. Red arrows indicate activating stimuli, while blue lines indicate inhibitory or antagonistic effects. MMP: matrix metalloproteinase; mt: mitochondria; P: phosphate; ROS: reactive oxygen species; SOD2: superoxide dismutase 2; VSMC: vascular smooth muscle cells.</div>

Oxidative Medicine and Cellular Longevity

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Figure 1: Superoxide Dismutase 2 (SOD2) in Vascular Calcification: A Focus on Vascular Smooth Muscle Cells, Calcification Pathogenesis, and Therapeutic Strategies 

Figure 1 | Superoxide Dismutase 2 (SOD2) in Vascular Calcification: A Focus on Vascular Smooth Muscle Cells, Calcification Pathogenesis, and Therapeutic Strategies 