Review Article

Natural Phytochemicals as Novel Therapeutic Strategies to Prevent and Treat Parkinson’s Disease: Current Knowledge and Future Perspectives

Figure 3

Intracellular targets of neuroprotective antioxidant phytochemicals by activation of Keap1/Nrf2/ARE signaling pathways to increase the expression of antioxidant enzymes. The modulation of these pathways by natural antioxidant phytochemicals such as chrysin, vanillin, asiatic acid (AA), ferulic acid (FA), thymoquinone (TQ), ellagic acid (EA), caffeic acid (CA), epigallocatechin-3-gallate (EGCG), α- and β-asarone, and theaflavin (TF).