Systems Biology and Chemoinformatics-Based Strategies to Explore the Biological Mechanism of Fugui Wenyang Decoction in Treating Vascular Dementia Rats

Figure 4

Component-target network of FGWYD. (Pink hexagons stand for FGWYD targets. Red, orange, yellow, green, blue, indigo, and purple circles stand for components of Morindae Officinalis Radix, Arum Ternatum Thunb., Radix Rhei Et Rhizome, Aconiti Lateralis Radix Praeparata, Cinnamomi Ramulus, Panax Ginseng C. A. Mey., and Panax Notoginseng (Burk.) F. H. Chen Ex C. Chow, respectively. Red, orange, and yellow diamonds stand for compounds of Zingiber Officinale Roscoe, Acoritataninowii Rhizoma, and Epimrdii Herba, respectively. Yellow diamond stands for common component of Morindae Officinalis Radix, Arum Ternatum Thunb., Radix Rhei Et Rhizome, Aconiti Lateralis Radix Praeparata, Cinnamomi Ramulus, Panax Ginseng C. A. Mey., Panax Notoginseng (Burk.) F. H. Chen Ex C. Chow, and Zingiber Officinale Roscoe. Green diamond stands for common component of Morindae Officinalis Radix, Aconiti Lateralis Radix Praeparata, Cinnamomi Ramulus, and Epimrdii Herba. Blue diamond stands for common component of Morindae Officinalis Radix, Panax Ginseng C. A. Mey., and Panax Notoginseng (Burk.) F. H. Chen Ex C. Chow. Indigo diamond stands for common component of Morindae Officinalis Radix, Panax Ginseng C. A. Mey., and Panax Notoginseng (Burk.) F. H. Chen Ex C. Chow. Purple diamond stands for common component of Arum Ternatum Thunb., Panax Ginseng C. A. Mey., Panax Notoginseng (Burk.) F. H. Chen Ex C. Chow, and Zingiber Officinale Roscoe. Red triangle stands for common component of Arum Ternatum Thunb. and Acoritataninowii Rhizoma. Orange triangle stands for common component of Panax Ginseng C. A. Mey., Acoritataninowii Rhizoma, and Epimrdii Herba. Yellow triangle stands for common component of Panax Notoginseng (Burk.) F. H. Chen Ex C. Chow and Epimrdii Herba. Green triangle stands for common component of Zingiber Officinale Roscoe and Epimrdii Herba. Blue triangle stands for common component of Acoritataninowii Rhizoma and Epimrdii Herba.)