Impact of Physical Activity on Oxidative Stress Markers in Patients with Metastatic Breast Cancer

Table 3

Change in antioxidant, prooxidant enzymes, and oxidative stress markers, ABLE Trial, 2016-2018.

Biomarkers	Baseline ()	After 6 months ()	^a
Antioxidant enzymes
CAT (μmol.min^-1.L^-1), mean (SD)	34.14 (18.66)	37.85 (18.70)	0.40
SOD (μmol.min^-1.L^-1), mean (SD)	9.17 (4.31)	9.00 (4.59)	0.54
Prooxidant enzymes
NADPH oxidase leucocytes (μmol.min^-1.mg^-1 of protein), mean (SD)	0.22 (0.06)	0.22 (0.06)	0.89
MPO plasma (μmol.min^-1.L^-1), mean (SD)	114.07 (58.03)	121.75 (51.49)	0.29
MPO leucocytes (μmol.min^-1.mg^-1 of prot), mean (SD)	15.90 (4.38)	15.76 (7.86)	0.74
Oxidative stress markers
8-OHdG (μg.L^-1), mean (SD)	17.13 (18.16)	17.72 (15.42)	0.46
AOPP (μmol.L^-1), mean (SD)	78.96 (55.20)	87.37 (55.88)	0.44

^aWilcoxon signed-rank test. CAT: catalase; SOD: superoxide dismutase; NADPH: nicotinamide adenine dinucleotide phosphate; MPO: myeloperoxidase; 8-OhdG: 8-hydroxydeoxyguanosine; AOPP: advanced oxidation protein products.