Promoting Nrf2/Sirt3-Dependent Mitophagy Suppresses Apoptosis in Nucleus Pulposus Cells and Protects against Intervertebral Disc Degeneration

Figure 4

t-BHQ was docked with the Nrf2 structure. Docking studies were performed as described in Materials and Methods: (a) the model of STA; (b) the ribbon model of the Nrf2 protein-protein complex; (c) 2D binding model between the t-BHQ and Nrf2 complex; (d) 3D docking analysis between the t-BHQ and Nrf2 complex.

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