Increased ROS-Dependent Fission of Mitochondria Causes Abnormal Morphology of the Cell Powerhouses in a Murine Model of Amyotrophic Lateral Sclerosis

<div>Three-dimensional visualization of the mitochondrial crista structure. TEM tomography of cervical spinal cord of wild-type and wobbler mice. (a) Exemplary image of a recorded plane of TEM tomography with reconstruction of mitochondrial membranes. Blue line represents the modulation of the outer mitochondrial membrane (OMM), while the green line modulates the inner mitochondrial membrane (IMM). (b) Front view and tilted view of the finally meshed 3D models of WT and WR mitochondria. 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Oxidative Medicine and Cellular Longevity

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Figure 3

Figure 3: Increased ROS-Dependent Fission of Mitochondria Causes Abnormal Morphology of the Cell Powerhouses in a Murine Model of Amyotrophic Lateral Sclerosis 

Figure 3 | Increased ROS-Dependent Fission of Mitochondria Causes Abnormal Morphology of the Cell Powerhouses in a Murine Model of Amyotrophic Lateral Sclerosis 