Limonin Inhibits IL-1<i>β</i>-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2

<div>The effect of limonin on the survival of chondrocytes <i>in vitro</i>. (a) The chemical structure of limonin. (b, c) The toxic effect of limonin on chondrocytes at different concentrations (0, 15, 30, 60, and 120 <i>μ</i>M) for 24 and 48 hrs. The viability of cells was assessed by CCK-8 assay. 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Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Limonin Inhibits IL-1<i>β</i>-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2 

Oxidative Medicine and Cellular Longevity

Limonin Inhibits IL-1β-Induced Inflammation and Catabolism in Chondrocytes and Ameliorates Osteoarthritis by Activating Nrf2

Figure 1