Research Article
κ Opioid Receptor Agonist Inhibits Myocardial Injury in Heart Failure Rats through Activating Nrf2/HO-1 Pathway and Regulating Ca2+-SERCA2a
Figure 1
κ-OR agonist improved cardiac function in HF rats and reduced myocardial injury. (a) Echocardiographic parameters: LVDs, LVDd, LVEF, and LVFS. (b) The natriuretic peptide contents of BNP and NT-proBNP detected by ELISA. (c) Pathological changes observed by HE staining ( μm). (d) Pathological examination of tissue fibrosis by Masson staining ( μm); .
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