Research Article
κ Opioid Receptor Agonist Inhibits Myocardial Injury in Heart Failure Rats through Activating Nrf2/HO-1 Pathway and Regulating Ca2+-SERCA2a
Figure 5
CaMKII agonist blocks the protective effects of κ-OR agonist on myocardium in HF rats. (a) Pathological changes in myocardial tissues observed by HE staining ( μm). (b) The tissue fibrosis was examined by Masson staining ( μm). (c) The myocardial apoptosis rate was detected by TUNEL staining ( μm). (d) The natriuretic peptide contents were determined by ELISA; .
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