Research Article
κ Opioid Receptor Agonist Inhibits Myocardial Injury in Heart Failure Rats through Activating Nrf2/HO-1 Pathway and Regulating Ca2+-SERCA2a
Figure 6
Nrf2 antagonist blocks the κ-OR-activated Ca2+-SERCA2a. The expression of SERCA2a, calcium-regulated proteins DHPR and Cav1.2 (a), phosphorylation of CaMKII and CREB (b), and the ERS-associated regulatory proteins (c) were detected by Western Blotting; .
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