Antioxidative and Anti-Inflammatory Effects of Lactobacillus plantarum ZS62 on Alcohol-Induced Subacute Hepatic Damage

Figure 5

Hepatic mRNA expressions of mice; c-Jun N-terminal kinase (JNK), extracellular regulated protein kinases (ERK), cyclooxygenase-1 (COX1), peroxisome proliferator-activated receptor-α (PPAR-α), nuclear factor erythroid-2 related factor 2 (Nrf2), hemeoxygenase-1 (HO-1), superoxide dismutase 1 (SOD1), superoxide dismutase 2 (SOD2), GSH-Px (glutathione peroxidase), catalase (CAT), and nicotinamide adenine dinucleotide phosphate (NADPH) mRNA. The different alphabets (^a–d) mean significant differences (). Control: mice without treatments except twice 0.85% saline treatment a day; model: mice treated with alcohol (56%, v/v, 0.13 mL/10 g _bw); alcohol+LDSB: mice treated with of Lactobacillus delbruechill subsp. Bulgaricus before alcohol treatment; alcohol+ZS62: mice treated with Lactobacillus plantrum ZS62 before alcohol treatment.