Deficiency of ROS-Activated TRPM2 Channel Protects Neurons from Cerebral Ischemia-Reperfusion Injury through Upregulating Autophagy

Figure 1

Time-lapse of ROS production under OGD-R treatment. (a) Primary cortical neurons treated with medium alone (CTRL) or 1 h of OGD plus different time (1 h, 2 h, or 3 h) of reperfusion (OGD-R) minus or plus NAC (5 mM) were stained with H2DCF-DA and subjected to FACS (number of ). (b) data from 2 independent experiments. Each experiment performed 2-3 biological replicates. ; ; one-way ANOVA with post hoc Tukey test.

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