Inhibition of Fatty Acid Metabolism Increases EPA and DHA Levels and Protects against Myocardial Ischaemia-Reperfusion Injury in Zucker Rats

Table 1

The effects of methyl-GBB administration on triglyceride, total cholesterol, ASAT and ALAT concentrations in fed rat plasma, and weight gain after 12 weeks of treatment.

	Zucker lean	Zucker fa/fa
		Control	Methyl-GBB 10 mg/kg
Triglycerides, mM		^#	^#
Total cholesterol, mg/100 ml		^#	^#
ASAT, U/l
ALAT, U/l		^#	^#
Body weight gain, g		^#	^#
Heart to body weight, mg/g		^#	^#
Liver to body weight, mg/g
Kidney to body weight, mg/g

Each value was calculated as the of 6 rats for triglyceride and total cholesterol concentrations, 8 rats for ASAT and ALAT levels, and 10 rats for body weight gain. ^#Significantly different from the Zucker lean group (ANOVA followed by Tukey’s test; ).