Shexiang Baoxin Pill for Acute Myocardial Infarction: Clinical Evidence and Molecular Mechanism of Antioxidative Stress
Table 1
Basic information of the included preclinical experiments.
ID
Animal species
Gender
Number of animals
Age
Weight
Intervention
Experimental duration
Experimental type
Luo X P 1999
SD rats (NR)
Male
49
NR
250-300 g
SBP
14 days
Pharmacodynamics
Xiang L 2013
SD rats (NR)
Male
56
NR
SBP, SFSBP, seven components
15 days
Metabonomics
Liu Q 2017
SD rats (SPF)
Male
81
NR
Ginsenosides in SBP
5 days
Metabonomics
Jiang P 2011
SD rats (NR)
Male
17
NR
SBP
4 days
Metabonomics
Yu F 2021
SD rats (SPF)
Male
6
7 weeks
200-230 g
SBP
15 days
Quantitative proteomics
Note: SD: Sprague-Dawley; SPF: specific pathogen-free; SBP: Shexiang Baoxin Pill; SFSBP: simplified formula of SBP; NR: not reported. Including muskone, ginsenoside, ginsenoside, cinnamic acid, cholic acid, bufalin, and borneol.