VDAC1 Conversely Correlates with Cytc Expression and Predicts Poor Prognosis in Human Breast Cancer Patients

Table 7

Univariate and multivariate analyses of predictive factors for disease free survival in TNBC.

		Univariate		Multivariate
		value	Hazard ratio, 95% CI	value	Hazard ratio, 95% CI
VDAC1 expression		0.001	4.616 (1.635-13.029)	0.009	4.018 (1.415-11.407)
High	61
Low	26
Age		0.802	0.921 (0.484-1.753)
≤50	49
>50	38
TNM stage		0.000	3.332 (1.757-6.317)	0.003	2.663 (1.381-5.135)
I/II	61
III	26
Lymph node metastasis		0.002	3.186 (1.504-6.747)
No	38
Yes	49
Histological grade		0.000	3.149 (1.660-5.974)	0.007	2.469 (1.28-4.762)
G1/G2	59
G3	28
Menopause		0.590	0.839 (0.444-1.587)
Before	43
After	44