Peroxisome Deficiency Dysregulates Fatty Acid Oxidization and Exacerbates Lipotoxicity in β Cells

Figure 2

Dysregulated expression of genes implicated in fatty acid metabolism are shown in Pex14 KD INS-1 cells. (a, b) The expression of FAO enzymes and Abcd3 was detected by q-PCR (a) and western blot analysis (b). , vs. the blank or si-NC group. (c) Fasn protein expression was detected by IF staining (×400), scale bar 50 μm. (d) Nile Red staining of INS-1 cells (×200). Scale bar 100 μm.

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