Research Article
ASC Speck Formation after Inflammasome Activation in Primary Human Keratinocytes
Figure 6
NLRP1 inflammasome blocking protects from cell death: hPKs were transfected with NLRP1 and NLRP3 siRNA and were irradiated with UVB (50 mJ/cm2). The absence of NLRP1 and partially of NLPR3 protected from cell death resulting in a reduction of LDH release. Data represent at least 3 independent experiments and are presented as the . Statistics: one-way ANOVA statistical test. Symbols for values used in the figures. , , and . NS: not significant.