Role of Calcium Signaling Pathway-Related Gene Regulatory Networks in Ischemic Stroke Based on Multiple WGCNA and Single-Cell Analysis

Figure 5

Cell type-specific regulons in the mouse brain vasculature. (a) Ranks of regulons in the mouse brain vasculature endothelial cells sorted based on regulon specificity scores (right) and the corresponding binding motifs of TFs. (b) Endothelial cells are highlighted as red dots in the tSNE plot. (c) The expression values of interesting genes are presented as green dots in the tSNE plot. (d–f) Same as (a–c) but for microglia. (g–i) Same as (a–c) but for oligodendrocytes. (j–l) Same as (a–c) but for fibroblasts.

(a)

(b)

(c)

(d)

(e)

(f)

(g)

(h)

(i)

(j)

(k)

(l)