Estrogen Replacement Therapy Induces Antioxidant and Longevity-Related Genes in Women after Medically Induced Menopause

Figure 4

(a) ERT after GnRH-induced menopause upregulates TP53 gene expression. (b) ERT restores basal levels of P21 gene expression after pharmacological-induced menopause. (c) SESN2 mRNA levels increase after ERT in 16 women of reproductive age who underwent GnRH-induced menopause. (d) ERT restores TERF2 mRNA levels after GnRH-induced menopause. Data are expressed as median and range with 95% CI for 16 women of reproductive age who underwent GnRH-induced menopause.

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