Research Article

RXRα Blocks Nerve Regeneration after Spinal Cord Injury by Targeting p66shc

Figure 3

Expression of p66shc before and after spinal cord injury. Immunofluorescence staining showed that there was no significant difference in the expression of RXRα before and after spinal cord injury (rat spinal cord tissue (a) and primary neurons cultured in vitro (b)), while p66shc was expressed at low levels before spinal cord injury and the expression significantly increased after spinal cord injury. p66shc was colocalized with RXRα. /group, scale bar: 50 or 100 μm.
(a)
(b)