Low-Grade Systemic Inflammation Interferes with Anabolic and Catabolic Characteristics of the Aged Human Skeletal Muscle

Figure 3

Increased proteasome activity at basal state in response to chronic LGSI in older adults. (a) Enzymtic determination of chymotrypsin-like proteasome activity ( in ESI and 10 in control). (b–e) Quantification of immunoproteasome (β1i, β2i, and β5i) and proteasome (β5) subunits by densitometry (results are expressed as ratio of each subunit to GAPDH) and representative western blots ( in ESI and 10 in control). Significant difference from basal (). ^#Significant difference between groups (). All data are presented as .

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