Polymethoxyflavones in Citrus Regulate Lipopolysaccharide-Induced Oscillating Decay of Circadian Rhythm Genes by Inhibiting <i>Nlrp3</i> Expression

<div>Preliminary verification of the mechanism by nobiletin-regulated circadian gene expression in BV-2 cells using the Nlrp3 inhibitor, INF39: (a) regulation of <i>Nlrp3</i> gene expression by LPS and INF39; (b) ELISA detection of Nlrp3 protein expression regulated by LPS and INF39; (c) effects of INF39-regulated circadian gene expression, as measured by qRT-PCR. 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Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Polymethoxyflavones in Citrus Regulate Lipopolysaccharide-Induced Oscillating Decay of Circadian Rhythm Genes by Inhibiting <i>Nlrp3</i> Expression 

Figure 6 | Polymethoxyflavones in Citrus Regulate Lipopolysaccharide-Induced Oscillating Decay of Circadian Rhythm Genes by Inhibiting Nlrp3 Expression 