Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by <i>Warburgia ugandensis</i> Extract through Mediating G<sub>0</sub>/G<sub>1</sub> Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation

<div>WUD impairs tumor growth in vivo. (a–d) CT26 CRC-bearing xenografted mice were intraperitoneally treated with PBS (model group) or DDP or WUD for 18 days, each with 6 animals/group. (a) Mouse body weights and (b) tumor volumes were measured during the treatment. (c) Tumor weights and (d) the photographs of tumors were measured at the end of the treatment. 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DDP: cisplatin 5 mg/kg, twice weekly; WUD-L: 57 mg/kg/d; WUD-M: 114 mg/kg/d; WUD-H: 228 mg/kg/d.</div>

Oxidative Medicine and Cellular Longevity

fig6

Figure 6

Figure 6: Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by <i>Warburgia ugandensis</i> Extract through Mediating G<sub>0</sub>/G<sub>1</sub> Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation 

Figure 6 | Inhibition of Growth of Colon Tumors and Proliferation of HT-29 Cells by Warburgia ugandensis Extract through Mediating G0/G1 Cell Cycle Arrest, Cell Apoptosis, and Intracellular ROS Generation 