Nrf2-ARE Signaling Partially Attenuates Lipopolysaccharide-Induced Mammary Lesions via Regulation of Oxidative and Organelle Stresses but Not Inflammatory Response in Mice

Figure 6

Effects of LPS and Nrf2 phenotype on mitochondrial-dependent apoptotic and endoplasmic reticulum stress. Effects of LPS and Nrf2 phenotype (+/+, +/-, and -/-) on relative mRNA abundance of (a) BAX, (b) Bcl-xl, (c) BAX/Bcl-xl, (d) GPR78, and (e) CHOP in the mammary gland of mice. In all panels, test was used to determine the differences between LPS and PBS treatments. Data represent the (). All data marked with or ^# represent a significant difference (), and marked with or ^## represent a highly significant difference ().

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