Toxic Prediction of Pyrrolizidine Alkaloids and Structure-Dependent Induction of Apoptosis in HepaRG Cells

<div>Chemical structures of the investigated PAs. Two classic structural types of PAs, which cover 4 different structures: retronecine type of twelve-membered cyclic diester (RTS), eleven-membered cyclic diester (MCT), noncyclic diester (RN), and platynecine-type (PLA).</div>

Oxidative Medicine and Cellular Longevity

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Figure 1

Figure 1: Toxic Prediction of Pyrrolizidine Alkaloids and Structure-Dependent Induction of Apoptosis in HepaRG Cells 