Toxic Prediction of Pyrrolizidine Alkaloids and Structure-Dependent Induction of Apoptosis in HepaRG Cells

<div>Effect of 4 PAs on the cell cycle in HepaRG cells (a, b). Distribution of cell cycle for HepaRG cells after treated with different concentrations (0, 50, and 200 <i>μ</i>M) of 4 PAs for 24 h. 10 <i>μ</i>M CPT was used as a positive control.</div>

Oxidative Medicine and Cellular Longevity

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Figure 4

Figure 4: Toxic Prediction of Pyrrolizidine Alkaloids and Structure-Dependent Induction of Apoptosis in HepaRG Cells 