Anti-inflammatory Effects of S. cumini Seed Extract on Gelatinase-B (MMP-9) Regulation against Hyperglycemic Cardiomyocyte Stress

Figure 7

(a) Matrix metalloproteinase-9 (MMP-9) and polyphenol binding energy interaction graph. The -axis represented various MSE polyphenols/doxycycline, and the -axis showed (-ve) binding energy. (b) Predicted binding mode of polyphenols and doxycycline to MMP-9 (gelatinase-B): docked structures of gallic acid (pink), p-hydroxybenzoic acid (dark green), ellagic acid (blue), kaempferol (gray), p-coumaric acid (orange), protocatechuic acid (yellow), sinapic acid (light green), caffeic acid (brown), ferulic acid (mustard), and quercetin (red) with MMP-9. (c) Docking pose of doxycycline with MMP-9.

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