Osthole-Loaded Nanoemulsion Enhances Brain Target in the Treatment of Alzheimer’s Disease via Intranasal Administration

Figure 8

Effect of OST-NE on L-Glu-induced apoptosis in SH-SY5Y cells by TUNEL staining: (a) control, (b) model (blank nanoemulsion+30 mmol/L L-Glu), (c) OST-NE (10 μmol/L)+L-Glu (30 mmol/L), (d) OST-NE (0.1 μmol/L)+L-Glu (30 mmol/L). Red: TUNEL-positive; blue: DAPI,  μm.

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(b)

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