Protective Effect of Biobran/MGN-3 against Sporadic Alzheimer’s Disease Mouse Model: Possible Role of Oxidative Stress and Apoptotic Pathways

Figure 12

Congo red—brain-stained sections of mice for amyloid plaques visualization in the cerebral cortex and hippocampus (). (a, g, i) represent the normal group showing no deposition of amyloid plaques. (b, h) represent the STZ group showing multifocal deposition in the cerebral cortex in the cerebral cortex and the hippocampus, respectively. (c, d, j) represent Biobran (50 mg/kg) in STZ-injected mice, showing multifocal scattered plaques. (e, k) represent Biobran (100 mg/kg) in STZ-injected mice, showing few deposition in the cerebral cortex and multifocal deposition in the hippocampus. (f, l) represent Biobran (200 mg/kg) in STZ-injected mice showing minute deposition of amyloid plaques.