Research Article

Cardiac Inflammation, Oxidative Stress, Nrf2 Expression, and Coagulation Events in Mice with Experimental Chronic Kidney Disease

Table 2

Plasma concentration of urea and creatinine and creatinine clearance, and urinary concentration of kidney injury molecule-1 (KIM-1) and neutrophil gelatinase-associated lipocalin (NGAL), and kidney DNA damage in control and adenine-treated mice.

Parameters/groupControlAdenine

Urea (mmol/l)
Creatinine (μmol/l)
Creatinine clearance (ml/min)
KIM-1 (pg/ml)
NGAL (pg/ml)
DNA migration in kidney (mm)

Values in the table are presented as the (). Adenine was added to the feed at a concentration of 0.2% , for 4 weeks. , , , and (control vs. adenine group).