Noninvasive Analysis Using Data-Independent Acquisition Mass Spectrometry: New Epidermal Proteins That Reveal Sex Differences in the Aging Process

Figure 5

(a) Pathway classification of differentially expressed proteins, the -axis represents the number of differentially expressed proteins, the -axis represents the pathway-annotated entries. (b) Pathway relationships; red and blue dots indicate up- and downregulated differential proteins, respectively. Purple dots indicate the top ten enriched pathways, darker dots indicate significant enrichment, lighter dots indicate enrichment but not significant, and larger areas indicate higher enrichment. The different color lines indicate the different pathway categories: blue for environmental information processing, purple for human disease, orange for metabolism, and yellow for organismal systems.

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