Pyrogallol-Phloroglucinol-6 6-Bieckol on Attenuates High-Fat Diet-Induced Hypertension by Modulating Endothelial-to-Mesenchymal Transition in the Aorta of Mice

Figure 3

(a) Fluorescent images showing MMP9, TGF-β, and pSMAD2/3 expression in the aorta of HFD-fed mice. (b–e) mRNA levels of EndMT-related molecules (b) MMP9, (c) TGF-β, (d) SMAD2, and (e) SMAD3 were determined in HFD-fed mice using qRT-PCR. (f–i) mRNA levels of EndMT-related molecules (f) MMP9, (g) TGF-β, (h) SMAD2, and (i) SMAD3 were determined in oxLDL-treated SVEC4–10 cells using qRT-PCR. vs. NFD/saline or PBS, ^#vs. HFD/saline or oxLDL/PBS.

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