The Beneficial Effects of Edible Kynurenic Acid from Marine Horseshoe Crab (Tachypleus tridentatus) on Obesity, Hyperlipidemia, and Gut Microbiota in High-Fat Diet-Fed Mice

Figure 4

Effects of KA on HFD-caused the changes in blood lipid levels in mice: (a) total cholesterol (TC) in serum; (b) triglyceride (TG) in serum; (c) low-density lipoprotein cholesterol (LDL-C) in serum; (d) high-density lipoprotein cholesterol (HDL-C) in serum; (e) coronary artery risk index (CRI); (f) atherosclerosis index (AI). In HFD mice, KAL and KAH significantly reduced serum TG level and significantly increased serum HDL-C, respectively. KAL and KAH significantly inhibited HFD-induced the increases of serum LDL-C, CRI, and AI levels, respectively. For HFD mice, these effects of KAL and KAH were similar to the effects of SV, respectively. Data were represented as ( for each group). , , and vs. NC mice. #, ##, and ### vs. HFD mice.

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