Decitabine Downregulates TIGAR to Induce Apoptosis and Autophagy in Myeloid Leukemia Cells

<div>DAC induces apoptosis by reducing p-Tyr and BCR-ABL. The 0.5 <i>μ</i>M of DAC and 0.1 <i>μ</i>M of Imatinib treatment of K562, K562/R, and K562/TIGAR cells is shown, and the level of p-Tyr was assessed by FCM. 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Oxidative Medicine and Cellular Longevity

fig4

Figure 4

Figure 4: Decitabine Downregulates TIGAR to Induce Apoptosis and Autophagy in Myeloid Leukemia Cells 