Melatonin Attenuates Diabetic Myocardial Microvascular Injury through Activating the AMPK/SIRT1 Signaling Pathway

<div>Melatonin prevented oxidant stress induced by HG in CMECs. (a) Flow cytometry to detect ROS production. (b) ROS mean fluorescent intensity. (c) MDA concentrations. (d) SOD activity. 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NG: normal glucose; HG: high glucose; M: mannitol; Mel: melatonin.</div>

Oxidative Medicine and Cellular Longevity

fig1

Figure 1

Figure 1: Melatonin Attenuates Diabetic Myocardial Microvascular Injury through Activating the AMPK/SIRT1 Signaling Pathway 