Green Tea (Camellia sinensis) Extract Increased Topoisomerase IIβ, Improved Antioxidant Defense, and Attenuated Cardiac Remodeling in an Acute Doxorubicin Toxicity Model

Table 6

Matrix metalloproteinase (MMP-2) activation in myocardial tissue forty-eight hours after injection of doxorubicin.

	C ()	GT ()	D ()	DGT ()
MMP-2at					0,85	0,49	0,68
MMP-2int.					0,16	0,23	0,02
MMP-2inat					0,93	0,95	0,24
MMP-2at/inat					0,81	0,79	0,72
MMP-2int/inat					0,09	0,13	0,53

Groups: C: control; GT: green tea; D: doxorubicin; DGT: doxorubicin+green tea. MMP-2a: active matrix metalloproteinase; MMP-2int: intermediary matrix metalloproteinase; MMP-2inat: inactive matrix metalloproteinase. Values are expressed in . value: two-way ANOVA. : value of interaction; : value of green tea; : value of doxorubicin. When we observed the interaction between factors (), we compared the groups. MMP-2int: , , , and .