Proteomic Analysis Revealed the Characteristics of Key Proteins Involved in the Regulation of Inflammatory Response, Leukocyte Transendothelial Migration, Phagocytosis, and Immune Process during Early Lung Blast Injury

Figure 1

Blast exposure caused severe lung injury, leukocyte infiltration, and the production of inflammatory factors in mice. (a, b) Pathological changes of acute lung injury caused by blast exposure at different time points. (c) The score of pathological changes of acute lung injury. (d–h) Representative images of Western blotting analysis and quantitative analysis of IL-1β, TNF-α, TGFβ1, and IL-10 expression in blast exposure-induced acute lung injury. All experiments were repeated at least three times. All data were expressed as () and analyzed by the one-way ANOVA test followed by Tukey’s test for multiple comparisons. Differences were considered statistically significant at . vs. the control (Ctrl) group.

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