Proteomic Analysis Revealed the Characteristics of Key Proteins Involved in the Regulation of Inflammatory Response, Leukocyte Transendothelial Migration, Phagocytosis, and Immune Process during Early Lung Blast Injury

Figure 2

Global proteomics analyses and the identification of differentially expressed proteins in blast exposure-induced lung injury at different time points. (a) Hierarchical clustering heatmap of the differentially expressed proteins in the lungs on at different time points after blast exposure. (b) Venn diagram showing the distribution of differentially expressed proteins among groups. Overlapping parts represented proteins that appear at different time points. (c–e) GO analysis of differentially expressed proteins in the lungs at different time points after blast exposure. (c) Biological process. (d) Cellular components. (e) Molecular functions. (f) KEGG analysis of differentially expressed proteins of mouse lungs at different time points after blast exposure. (g) Network analysis of all obtained differentially expressed proteins. The connection was illustrated using the web-based tool STRING.

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