Proteomic Analysis Revealed the Characteristics of Key Proteins Involved in the Regulation of Inflammatory Response, Leukocyte Transendothelial Migration, Phagocytosis, and Immune Process during Early Lung Blast Injury

Figure 7

Blast exposure significantly changed the expression of crucial proteins in immune system process. (a) Western blot analysis of the expression of key proteins related to immune system process after blast exposure. (b) Lbp expression levels were significantly increased at 24 h, 48 h, 72 h, and 1 week after blast exposure compared with the control (Ctrl) group. (c) Hsp90ab1 expression levels were significantly increased at 12 h and 24 h after blast exposure compared with the control group. (d) CD74 expression levels were significantly increased at 12 h, 24 h, 48 h, and 72 h after blast exposure compared with the control group. (e) Ltf expression levels were significantly increased at 12 h and 24 h after blast exposure compared with the control group. (f) Ankrd17 expression levels were significantly increased at 24 h, 48 h, 72 h, and 1 week after blast exposure compared with the control group. All experiments were repeated at least three times. All data were expressed as () and analyzed by the one-way ANOVA test, followed by Tukey’s test for multiple comparisons. Differences were considered statistically significant at for all analyses. vs. the control group.

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