Review Article
Roles of Therapeutic Bioactive Compounds in Hepatocellular Carcinoma
Figure 6
Cytochrome P450 contribution to human diseases caused by ROS and produced as a result of substrate metabolism by CYP 450s which cause elevations in protein and nucleic acid levels and cause lipid modifications. These modified products further lead to lipid peroxidation processes and also cause DNA damage which in turn causes cancer.